CBD and the Endocannabinoid System
- Published20 Oct 2021
- Source BrainFacts/SfN
Products containing cannabidiol, or CBD, have become wildly popular in recent years. However, many of the purported therapeutic benefits remain unproven. Existing research hints at some benefits, but only time and more research will paint a fuller picture.
This is a video from the 2021 Brain Awareness Video Contest.
Created by Andrew Solway.
CONTENT PROVIDED BY
BrainFacts/SfN
Transcript
CBD, CBD,
a billion-dollar industry
But despite the popularity
could it really be the next big therapy?
CBD, CBD,
what’s it mean to you and me?
Listen up and we’ll tell you why
and how it works on us inside
First off, it’s a cannabinoid,
but what does that mean?
It’s a type of chemical,
kind of like we make in our own bodies
There’s one we make that’s called anandamide
or AEA
It’s a chemical messenger
synthesized postsynaptically
CBD, CBD,
what’s it mean to you and me?
Listen up and we’ll tell you why
and how it works on us inside
CBD boosts anandamide
by inhibiting FAAH
Boost its concentration
so it can bind to
CB-1 and CB-2
CB-1 is in the CNS,
CB-2 in the immune,
and depending on where they go
will determine what they do
Anti-seizure, anti-anxiety, antipsychotic,
Anti-inflammatory, antioxidant, anti-craving
If it really works,
Wouldn’t that be amazing?
Bu for which of these conditions
Is it FDA approved?
For pediatric seizures only.
There’s so much more research left to do
CBD, CBD,
Wild west of homeopathy
But it could change medicine
With a little help from you and me
NIH, CDC,
Scientific community
It’s up to you to show the true
Effects of CBD
CBD, CBD,
What’s it mean to you and me?
It’s up to you to show the true
Effects of CBD
It’s up to you to show the true
Effects of CBD
a billion-dollar industry
But despite the popularity
could it really be the next big therapy?
CBD, CBD,
what’s it mean to you and me?
Listen up and we’ll tell you why
and how it works on us inside
First off, it’s a cannabinoid,
but what does that mean?
It’s a type of chemical,
kind of like we make in our own bodies
There’s one we make that’s called anandamide
or AEA
It’s a chemical messenger
synthesized postsynaptically
CBD, CBD,
what’s it mean to you and me?
Listen up and we’ll tell you why
and how it works on us inside
CBD boosts anandamide
by inhibiting FAAH
Boost its concentration
so it can bind to
CB-1 and CB-2
CB-1 is in the CNS,
CB-2 in the immune,
and depending on where they go
will determine what they do
Anti-seizure, anti-anxiety, antipsychotic,
Anti-inflammatory, antioxidant, anti-craving
If it really works,
Wouldn’t that be amazing?
Bu for which of these conditions
Is it FDA approved?
For pediatric seizures only.
There’s so much more research left to do
CBD, CBD,
Wild west of homeopathy
But it could change medicine
With a little help from you and me
NIH, CDC,
Scientific community
It’s up to you to show the true
Effects of CBD
CBD, CBD,
What’s it mean to you and me?
It’s up to you to show the true
Effects of CBD
It’s up to you to show the true
Effects of CBD
